List of Nightfall unique items by drop location

Unique items in italics drop from non-boss monsters

Throne of Secrets
Each of the unique items in the Throne of Secrets is obtained from collectors in exchange for one Book of Secrets instead of dropping from a boss.

Domain of Anguish

 * 1) Nihil's Daggers are only confirmed to drop from a single Fury Titan in the fourth chamber.
 * 2) Each of the three Paragon Stygian items is dropped by one or more unspecified types of Stygian Lord.