From Guild Wars Wiki

Warning: Running Guild Wars on a non-Windows operating system, or with any other computer which does not meet the system requirements, is completely unsupported by ArenaNet and NCSoft.

[edit] Installing Wine on SourceMage system

Use the following command to install pre-compiled Wine SourceMage system:

cast wine

Continue on Guild Wars on Wine to complet the GuildWars client installation.

[edit] SourceMage notes

Noting right now.