Lords of Anguish

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Spoiler alert: The following text contains spoilers relating to the story of Guild Wars Nightfall.

The Lords of Anguish are the four demonic overlords who serve Mallyx the Unyielding and lead the forces of opposition to Kormir's newly established rule over the Realm of Torment. They are based in the Domain of Anguish:

Each lord will only appear after completing all of the prerequisite quests for the subregion; three appear with an entourage of demons, while the Dreadspawn Maw's death requires killing six Smothering Tendrils. You can only reach Mallyx, the target of the quest, Mallyx the Unyielding, by killing the four overlords.