Shrines are not active by default, but most explorable areas include a shrine close enough to each entrance portal that it is activated as soon as the party enters the area. Further shrines can be activated by approaching them, a white ball of light will appear as they activate. Most will activate near aggro range.
It can be useful to continually activate shrines near the front line of adventure, as the nearest activated shrine will receive the wiped party for resurrection.
The amenities of the shrines vary depending on which campaign they are in.
 Functions and services
- Prophecies: Some also contain a statue to a god, allowing players to receive blessings. Most of these activate when within party range.
- Factions: Most also contain statues. In faction-controlled explorable areas, Kurzick and Luxon Priests will dispense bounty-like blessings. Most of these activate when within spirit range.
- Nightfall: All contain statues (except the ones in the Realm of Torment), as well as a NPC who will give a bounty. Most of these activate when within earshot.
- Eye of the North: No statues, with a Norn, Ebon Vanguard, or Asuran NPC, depending on the region, who will give a bounty-like blessing. Most of these activate when within earshot.
- Guild versus Guild: Resurrects all team members that aren't at maximum Death Penalty every 2 minutes by the match clock.
- Heroes' Ascent: Resurrects players on Relic Run maps and in the Hall of Heroes at specific intervals.
- Alliance battles: Resurrects players twenty seconds after death. Shrines not guarded by a Base Defender must be captured.
- When resurrected, all shrines provide you with Untouchable.
- Grenth allows the existence of resurrection, especially for heroes so they may continue obtaining Favor. However, he has been known to withhold such a blessing (likely those he deems unworthy).
- Shrines are generally inactive during missions. Most mission areas that do not double as explorable areas (e.g., missions in Prophecies) do not have shrines at all.
- A few shrines exist that have been completely destroyed, and therefore can never be used. (ie: west side of the catacombs in Prophecies)
- In some cases you must persuade or pay the keepers of shrine to activate it. If you don't, and you don't find a free shrine before a party wipe, you will be sent back to the last town or outpost you visited. This is generally a faction allegiance issue in Factions.
- In Eye of the North's Depths of Tyria region, the Beacon of Droknar, an object-like NPC that appears as a free-floating ball of "active shrine resurrection light", provides both resurrection and Deldrimor blessing services.
- Nearly all of Factions and Nightfall's statues are attached to shrines, thus, shrines are a handy indicator of the current status of the Favor of the Gods. If the world has favor, a god's statue will be radiating their full glory.
- Each resurrection shrine has a different distance your party can be from it to show the "lighting" animation.
The statue at the shrine pictured above is of the god Balthazar, whose burning fire and shining eyes indicate that the world has the Favor of the Gods in both cases.