Region
From Guild Wars Wiki
A region is a named collection of different types of locations, including towns, outposts, Missions, Dungeons and explorable areas with a common theme. This theme can be seen as represented by the regions loading screen.
Regions usually have a shared set of creatures, a key and chest pair, and a common section in the quest log. Sometimes one or more of these factors are instead shared by a smaller set of locations that are not technically a region; such are known as subregions.
The skills Edification and Heart of the Norn are triggered by being in the Tarnished Coast and Far Shiverpeaks regions, respectively.

